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Can an extra nerve block double down on Post-Surgery pain relief?

NCT ID NCT07788911

Symptom relief Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This study looks at two ways to manage pain after laparoscopic gallbladder removal. Some patients receive a nerve block on the side of the abdomen, while others get that same block plus an additional block near the midline. Researchers will compare pain scores, opioid use, and side effects in the first 24 hours after surgery to see if the combined approach offers better relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Bilateral external oblique intercostal plane block with or without bilateral rectus sheath block, using bupivacaine
What this could lead to
If adding a rectus sheath block improves pain relief, it could lead to better recovery and less opioid use after gallbladder surgery.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The choice of block was made by doctors, not randomly assigned, which may bias results. Also, the study is small and may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

104 people

The number who actually took part.

Started

May 2025

Finished

Apr 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients aged 18 to 70 years with American Society of Anesthesiologists physical status I to III who underwent laparoscopic cholecystectomy were included. Participants were observed in two cohorts according to the regional block technique selected and performed by the attending anesthesiologist as part of routine clinical care.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 70 years * American Society of Anesthesiologists physical status I to III * Scheduled to undergo laparoscopic cholecystectomy * Received bilateral EOIPB alone or bilateral EOIPB combined with bilateral RSB as part of routine clinical care * Provided written informed consent to participate Exclusion Criteria: * Contraindication to regional block procedures, including coagulopathy, anticoagulant use, or local infection at the needle insertion site * Known severe cardiovascular, renal, or hepatic disease * Life-threatening hematological disease * Neurological disease or psychiatric disorder * Known allergy to the medications used in the study or to amide-type local anesthetics * History of chronic pain * History of narcotic substance or alcohol dependence * Body mass index of 35 kg/m² or greater * Pregnancy * Refusal to participate

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain

Contacts and locations

Locations

  • Bakirkoy Dr. Sadi Konuk Training and Research Hospital

    Istanbul, 34147, Turkey (Türkiye)

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