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New study tests which root canal cleaning method heals teeth faster

NCT ID NCT07249450

Symptom relief Sponsor: Hilal Çuhadar Beşiroğlu Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 42 adults with infected single-rooted teeth to see if using sonic or ultrasonic tools to clean the root canal helps the tooth heal better than the standard method. Participants got one of three cleaning techniques during their root canal, and the size of the infection was measured with 3D scans before and 6 months after treatment. The goal was to find out if the newer methods lead to faster or more complete healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Mar 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

13 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria:• American Society of Anesthesiologists physical status classification system (ASA) class I and II * Individuals between 13 and 65 years of age * Good oral hygiene Tooth-related: * Single-rooted teeth * Sufficient amount of coronal tooth structure * Probing depth of ≤ 4 mm * Presence of Apical periodontitis (AP) on radiographs * Asymptomatic teeth * Periapical Index (PAI) score ≥ 3 * Negative response to pulp vitality tests * Mature teeth Exclusion Criteria:• ASA class III or higher * Pregnancy or lactation * Individuals with mental retardation * Allergy to Sodium hypochlorite (NaOCl), Chlorhexidine (CHX), or latex Tooth-related: * Extensive structural loss that cannot be restored with a filling * Presence of subgingival caries * Teeth previously treated with root canal therapy * Fractured or cracked teeth due to trauma * Non-vital teeth without radiographic evidence of AP * Immature teeth * Positive response to pulp vitality tests * Presence of internal or external root resorption detected on radiographs * Increased mobility due to insufficient bone support

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Conditions

The condition(s) this trial relates to.

periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Apical periodontitis

Contacts and locations

Locations

  • Istanbul Aydın University Faculty of Dentistry

    Istanbul, 34303, Turkey (Türkiye)

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