Jaw surgery showdown: three drugs battle for best visibility and least bleeding
NCT ID NCT06093893
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study compared three common blood pressure-lowering drugs—dexmedetomidine, nicardipine, and labetalol—given during jaw surgery to see which one helps surgeons see better and reduces blood loss. 90 healthy adults having jaw surgery at Boston Medical Center were randomly assigned to one of the three drugs. The goal is to find the safest and most effective option for this type of surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine, Nicardipine, Labetalol
What this could lead to
If successful, this could help surgeons choose the best drug for clearer visibility and less bleeding during jaw surgery.
What could go wrong
This is a small, completed Phase 4 trial with only 90 participants, so results may not apply to all patients or surgeries. Each drug also has its own side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Medical Center
Boston, Massachusetts, 02118, United States