Could a Pre-Surgery painkiller make jaw surgery recovery easier?

NCT ID NCT07571252

Not yet recruiting Symptom relief Sponsor: University of Puerto Rico Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests whether giving acetaminophen or ibuprofen before jaw surgery can lower pain after the operation. 72 adults having specific jaw procedures will be split into three groups: one gets IV acetaminophen, one gets IV ibuprofen, and one gets standard care without pre-surgery medication. Researchers will measure pain scores and how much extra pain medicine is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: acetaminophen and ibuprofen (given intravenously before surgery)
What this could lead to: If it works, this could point toward a standard way to reduce pain and the need for rescue painkillers after jaw surgery.
What could go wrong: This is a small, early-phase trial (72 people) testing a common approach, so results may not be dramatic or change practice widely. Pain is subjective and hard to measure precisely.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORTHOGNATHIC SURGERY POST-OPERATIVE PAIN

Contacts and locations

Locations

Administración de Servicios Médicos (ASEM)

San Juan, 00936, Puerto Rico

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