Could a Pre-Surgery painkiller make jaw surgery recovery easier?

NCT ID NCT07571252

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving acetaminophen or ibuprofen before jaw surgery can lower pain after the operation. 72 adults having specific jaw procedures will be split into three groups: one gets IV acetaminophen, one gets IV ibuprofen, and one gets standard care without pre-surgery medication. Researchers will measure pain scores and how much extra pain medicine is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

acetaminophen and ibuprofen (given intravenously before surgery)

What this could lead to

If it works, this could point toward a standard way to reduce pain and the need for rescue painkillers after jaw surgery.

What could go wrong

This is a small, early-phase trial (72 people) testing a common approach, so results may not be dramatic or change practice widely. Pain is subjective and hard to measure precisely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Administración de Servicios Médicos (ASEM)

    San Juan, 00936, Puerto Rico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••