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Can routine monitoring predict dangerous reflexes during jaw surgery?

NCT ID NCT07726251

Knowledge-focused Sponsor: Kırıkkale University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study observes adults aged 18 to 40 undergoing bimaxillary orthognathic surgery (corrective jaw surgery) to track how heart rate, blood pressure, and oxygen levels change during the procedure. Researchers will also look for the trigeminocardiac reflex, a sudden drop in heart rate that can occur during facial surgery. No extra tests or treatments are given—only standard monitoring data is used. The goal is to help surgeons recognize and manage these changes earlier.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help surgeons anticipate and manage sudden drops in heart rate or blood pressure during jaw surgery.
What could go wrong
This is a small observational study with only 18 participants, so findings may not apply to all patients or surgical settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 18 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult patients aged 18-40 years who are scheduled to undergo bimaxillary orthognathic surgery at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kırıkkale University. Eligible participants who provide written informed consent will be enrolled in this prospective observational cohort study. During surgery, routinely monitored intraoperative hemodynamic parameters and the occurrence of the trigeminocardiac reflex (TCR) will be evaluated according to the different stages of the surgical procedure.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-40 years. * Patients with an indication for bimaxillary orthognathic surgery. * Patients with complete routine intraoperative hemodynamic monitoring data. * Patients who provide written informed consent to participate in the study. Exclusion Criteria: * Patients without an indication for bimaxillary orthognathic surgery. * Individuals younger than 18 years or older than 40 years. * Patients with known cardiovascular disease, including arrhythmia, heart failure, coronary artery disease, or other significant cardiovascular disorders. * Patients with systemic diseases, including diabetes mellitus, hypertension, thyroid disorders, or other significant systemic conditions. * Patients with diagnosed psychiatric disorders. * Patients with incomplete or irregularly recorded intraoperative hemodynamic monitoring data. * Individuals who refuse to participate or do not provide written informed consent.

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Conditions

The condition(s) this trial relates to.

Intraoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemodynamic Orthognathic surgery Trigeminocardiac reflex

How to take part

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  1. The places running it

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  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Kırıkkale Univesity Faculty of Dentistry

    RECRUITING

    Kirikkale, Kırıkkale, 71450, Turkey (Türkiye)

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