Head-to-Head: which new heart valve works best?

NCT ID NCT06470022

First seen May 08, 2026 · Last updated May 08, 2026

Summary

This study compares two newer heart valve devices (Evolut FX and Sapien 3 Ultra Resilia) in people with aortic stenosis, a condition where the heart's main valve narrows. About 1,346 participants will be randomly assigned to receive one of the valves. The main goal is to see if one device is better at preventing death, stroke, valve leakage, or valve damage over the first year, with follow-up lasting up to 10 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of cardiology, Aarhus University Hospital

    RECRUITING

    Aarhus, 8200, Denmark

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.