Placebo power: cutting opioids without extra pain

NCT ID NCT05351333

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a method called conditioning open-label placebo (COLP) to help patients with spinal cord injury, multiple injuries, or burns use fewer opioids while still getting the same pain relief. About 66 adults in intensive rehab will receive a placebo alongside their regular opioid treatment. The goal is to reduce side effects and addiction risk without sacrificing pain control.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Spaulding Rehabilitation Hospital

    Charlestown, Massachusetts, 02129, United States

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Other studies related to the condition(s) this trial covers.