New drug may help gut wake up faster after colon surgery

NCT ID NCT07271875

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a newer drug, sugammadex, helps the bowels recover faster after colorectal surgery compared to an older drug combination (neostigmine/atropine). 560 adults having elective colorectal surgery will be randomly assigned to receive one of the two drugs at the end of surgery. The main goal is to see if more patients in the sugammadex group regain normal bowel function within 72 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Sugammadex and Neostigmine + Atropine
What this could lead to
If sugammadex works better, it could mean faster bowel recovery, less nausea, and shorter hospital stays after colorectal surgery.
What could go wrong
This is a single-center trial that hasn't started yet. Results may not apply to all hospitals, and the benefit over standard care may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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