Cocoa and exercise: a sweet combo for stronger seniors?
NCT ID NCT07161726
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding a cocoa supplement to a regular exercise program helps older adults (55+) with slow walking speed improve their physical performance and muscle strength more than exercise alone. Participants will be randomly assigned to receive either cocoa or a placebo alongside their exercise routine. The goal is to find a simple, tasty way to boost the benefits of staying active.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 55 years and older * Slow walking speed of \< 1m/s * Willingness to be randomized to either treatment group * Willingness to participate in all study procedures (muscle biopsy will be optional) Exclusion Criteria: * Failure to provide informed consent; * Regular consumption of flavanol and/or cocoa supplements * Current involvement in supervised rehabilitation/exercise training program * Absolute contraindication(s) to exercise training according to American College of Sports Medicine guidelines \[17\] * Daytime average of systolic blood pressure ≥ 180/100mm Hg. * Refusal to stop blood thinners such as baby aspirin dose. * Peripheral vascular disease; peripheral neuropathy; retinopathy * Severe cardiac disease, including NYHA Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest, use of a cardiac defibrillator, or uncontrolled angina; * Myocardial infarction or stroke within past year * Significant cognitive impairment, including known dementia diagnosis or a Mini-Mental State Examination exam score \< 24 * Progressive, degenerative neurologic disease, e.g., Parkinson's Disease, multiple sclerosis; * Severe rheumatologic or orthopedic diseases, e.g., awaiting joint replacement, active inflammatory disease; * Severe pulmonary disease, requiring either steroid pills or injections or the use of supplemental oxygen; * Hip fracture, hip or knee replacement, or spinal surgery within past 4 months; * Other significant co-morbid conditions that would impair ability to participate in the exercise-based intervention * Simultaneous participation in another interventional trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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