Why does exercise help some seniors more than others? new study aims to find out

NCT ID NCT06940037

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at why older adults respond differently to strength training. Researchers will enroll 300 people aged 65 and older who are at risk for mobility problems. Participants will either do progressive resistance training three times a week or attend weekly health education classes. The goal is to understand how aging biology affects changes in physical function and blood sugar control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Progressive resistance training (strength exercise) and health education classes
What this could lead to: If successful, this could help tailor exercise programs for older adults to maximize mobility and metabolic benefits.
What could go wrong: This is an observational-style trial without a drug or cure; it measures variability and may not lead to a direct treatment. Results depend on participant adherence and may not apply to all older adults.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING MOBILITY DISABILITY

Contacts and locations

Locations

Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University
RECRUITING

Boston, Massachusetts, 02111, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States

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