Heart bypass patients: does a stronger blood thinner keep grafts working longer?
NCT ID NCT04783701
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether taking two blood thinners (ticagrelor plus aspirin) is better than aspirin alone for keeping bypass grafts open in people who had heart surgery after a heart attack. About 360 participants will be followed for 1 to 3 years, and their grafts will be checked with a special CT scan. The goal is to see if the stronger blood-thinning regimen reduces graft blockages.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ticagrelor (antiplatelet drug) plus aspirin, compared to aspirin alone
What this could lead to
If it works, this could show that adding ticagrelor to aspirin helps keep bypass grafts open longer after heart surgery, potentially reducing the need for repeat procedures.
What could go wrong
This is a relatively small, early-phase study (360 participants) and results may not apply to all patients. The benefit of dual therapy must be weighed against a higher risk of bleeding.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dep of Vascular and Thoracic Surgery
ACTIVE_NOT_RECRUITINGÖrebro, Sweden
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Department of Cardiothoracic Surgery Karolinska University Hospital
ENROLLING_BY_INVITATIONStockholm, Sweden
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Department of Heart Disease, Haukeland University Hospital
ENROLLING_BY_INVITATIONBergen, Norway
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Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine
ENROLLING_BY_INVITATIONGothenburg, Sweden
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St Olavs University Hospital
NOT_YET_RECRUITINGTrondheim, Norway
Contact Email: •••••@•••••
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University Hospital Linköping
RECRUITINGLinköping, Östergötland County, 58185, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••