Could a probiotic tame Chemo's worst side effects?
NCT ID NCT07152886
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a probiotic called Clostridium butyricum can reduce severe diarrhea and other side effects in people getting chemotherapy for colorectal cancer. About 238 adults who had surgery for colorectal cancer and need chemo will take either the probiotic or a placebo. The main goal is to see if the probiotic lowers the chance of severe diarrhea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Clostridium butyricum capsules (a probiotic)
What this could lead to
If it works, this could offer a simple probiotic to ease severe diarrhea and other side effects during chemotherapy for colorectal cancer.
What could go wrong
This is a phase 4 trial, but it hasn't started yet. The probiotic may not reduce side effects more than a placebo, and results may not apply to all chemo regimens.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Affiliated Hospital of Qingdao University
Qingdao, Shandong, 266071, China
Contact