New Clot-Busting devices aim to save limbs and lives

NCT ID NCT07350499

Recruiting now Disease control Sponsor: Imperative Care, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 4 times

Summary

This study is testing two catheter-based devices, Symphony and Prodigy, that remove blood clots from blood vessels in the legs, arms, or lungs. Researchers want to see if these devices can safely restore blood flow and prevent serious outcomes like amputation or heart strain. The trial will follow 750 adults for up to 30 days to check how well the devices work and if there are any complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Symphony and Prodigy thrombectomy systems (catheter-based devices that remove blood clots)
What this could lead to: If successful, these devices could offer a safer, more effective way to remove dangerous blood clots, potentially reducing the need for major surgery or long-term disability.
What could go wrong: This is an early-stage study with 750 participants, so results may not apply to everyone. There are risks of bleeding, vessel damage, or the device not fully clearing the clot.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

arterial occlusion pulmonary embolism Thromboembolism thrombotic disease venous thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTERIAL THROMBOEMBOLISM PULMONARY EMBOLISM VENOUS THROMBOEMBOLISM

Contacts and locations

Locations

BayCare Health - St. Joseph Hospital
RECRUITING

Tampa, Florida, 33607, United States
Huntsville Hospital
RECRUITING

Huntsville, Alabama, 35801, United States
Mercy Health
RECRUITING

Cincinnati, Ohio, 45242, United States
Midwest Cardiovascular Institute
RECRUITING

Naperville, Illinois, 60540, United States
Mount Sinai Hospital
RECRUITING

New York, New York, 10029, United States
Profound Research
RECRUITING

Munster, Indiana, 46321, United States
Sentara Norfolk General Hospital
RECRUITING

Norfolk, Virginia, 23502, United States
University At Buffalo
RECRUITING

Buffalo, New York, 14203, United States

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