Experimental antibody shows promise in targeting leukemia cells

NCT ID NCT02860676

First seen Jan 05, 2026 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tested the safety of an experimental drug called cirmtuzumab in 3 people with chronic lymphocytic leukemia (CLL) who had already received the drug before. Cirmtuzumab is a lab-made antibody that attaches to a protein called ROR1 found on CLL cells, aiming to block their growth while sparing healthy cells. The goal was to see if giving the drug for 6 to 12 months is safe and tolerable.

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Contacts and locations

Locations

  • UC San Diego Moores Cancer Center

    La Jolla, California, 92093, United States

Conditions

Explore the condition pages connected to this study.