Could taking your UC meds at the right time of day boost their power?

NCT ID NCT05213234

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether taking a common ulcerative colitis medication (5-ASA) at a specific time of day—morning or evening—can better reduce hidden inflammation. Thirty-two adults with inactive UC will try both timing schedules over three months. Researchers will measure inflammation markers, drug levels in the gut, and sleep patterns.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

5-aminosalicylic acid (5-ASA) taken at different times of day

What this could lead to

If it works, this could show that simply changing when you take your medication can better control inflammation in ulcerative colitis.

What could go wrong

This is a small, early-phase trial with only 32 people. The benefit may be small or not apply to everyone. It does not test a new drug, just timing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60068, United States

  • The Medical University of South Carolina

    Charleston, South Carolina, 29425, United States