Could taking your UC meds at the right time of day boost their power?

NCT ID NCT05213234

Ongoing Disease control Sponsor: Rush University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether taking a common ulcerative colitis medication (5-ASA) at a specific time of day—morning or evening—can better reduce hidden inflammation. Thirty-two adults with inactive UC will try both timing schedules over three months. Researchers will measure inflammation markers, drug levels in the gut, and sleep patterns.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 5-aminosalicylic acid (5-ASA) taken at different times of day
What this could lead to: If it works, this could show that simply changing when you take your medication can better control inflammation in ulcerative colitis.
What could go wrong: This is a small, early-phase trial with only 32 people. The benefit may be small or not apply to everyone. It does not test a new drug, just timing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS

Contacts and locations

Locations

Rush University Medical Center

Chicago, Illinois, 60068, United States
The Medical University of South Carolina

Charleston, South Carolina, 29425, United States

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