New study tests two procedures for chronic migraine relief

NCT ID NCT07395908

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two treatments for chronic migraine: a nerve block and a radiofrequency procedure. Researchers will measure blood levels of migraine-related proteins (CGRP and PACAP38) before and one month after treatment. The goal is to see which procedure works better and whether these biomarkers can predict success. 100 adults with chronic migraine are enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Greater occipital nerve block and pulse radiofrequency
What this could lead to
If successful, this could point toward a more effective, biomarker-guided treatment for chronic migraine.
What could go wrong
This is a small, early-stage study with no control group, so results may not apply broadly. The treatments are procedures, not drugs, and long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Adnan Menderes University Efeler / Aydın

    Aydin, 09100, Turkey (Türkiye)

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