New study tests two procedures for chronic migraine relief
NCT ID NCT07395908
First seen Feb 15, 2026 · Last updated Jun 22, 2026 · Updated 24 times
Summary
This study compares two treatments—nerve block and radiofrequency—for chronic migraine in 100 adults. Researchers will measure blood levels of migraine-related chemicals (CGRP and PACAP38) before and one month after treatment to see which procedure works better. The goal is to find a more effective way to ease chronic migraine pain.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Adnan Menderes University Efeler / Aydın
Aydin, 09100, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Greater occipital nerve block and pulse radiofrequency
What this could lead to
If successful, this could point toward more effective, biomarker-guided treatments for chronic migraine.
What could go wrong
This is a small, early-stage study with no control group. Results may not apply to all migraine patients, and the treatments carry risks like infection or nerve damage.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.