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Could a nutrient in eggs boost brainpower in starving kids?

NCT ID NCT06154174

Ongoing Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests whether adding choline to a peanut-based therapeutic food improves cognitive development in 1,500 Malawian children aged 6-59 months with severe acute malnutrition. Half get standard food, half get food with extra choline. All also receive amoxicillin. The goal is to see if choline can help their brains develop better during recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
choline added to ready-to-use therapeutic food
What this could lead to
If it works, this could point toward a simple, low-cost way to boost brain development in children recovering from severe malnutrition.
What could go wrong
This is a large but early-stage trial; the added choline may not improve cognition more than standard food. The study is in one country, so results may not apply everywhere.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cachexia Cognitive Dysfunction kwashiorkor nutritional deficiency disease protein-energy malnutrition Severe Acute Malnutrition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE IMPAIRMENT KWASHIORKOR SEVERE ACUTE MALNUTRITION WASTING

Contacts and locations

Locations

  • Chikonde

    Chikonde, Mulanje, Malawi

  • Chipolonga

    Chipolonga, Machinga, Malawi

  • Makhwira

    Makhwira, Chikwawa, Malawi

  • Mbiza

    Mbiza, Mulanje, Malawi

  • Milonde

    Milonde, Mulanje, Malawi

  • Mitondo

    Mitondo, Chikwawa, Malawi

  • Muloza

    Muloza, Mulanje, Malawi

  • Namasalima

    Namasalima, Mulanje, Malawi

  • Naphimba

    Naphimba, Mulanje, Malawi

  • Nkhate

    Nkhate, Chikwawa, Malawi

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