Starving cancer cells: could cholesterol drugs slow pancreatic tumors?

NCT ID NCT04862260

First seen Mar 29, 2026 · Last updated May 28, 2026 · Updated 8 times

Summary

This early study tests whether adding three cholesterol-lowering drugs (atorvastatin, ezetimibe, and evolocumab) to standard chemotherapy can slow or stop pancreatic cancer growth. Cancer cells need lots of cholesterol to grow, and this approach aims to starve them. The trial includes 3 adults with advanced or metastatic pancreatic cancer who have not yet had treatment. The main goal is to check if the drug combination is safe and feasible.

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Contacts and locations

Locations

  • CHU de Québec-Université Laval

    Québec, Quebec, G1R 2J6, Canada

  • CHUM

    Montreal, Quebec, H2X 0A9, Canada

Conditions

Explore the condition pages connected to this study.