Cholera vaccine vaxchora put to the test in immune response study

NCT ID NCT03251495

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tested the oral cholera vaccine Vaxchora in 34 healthy adults to see how well it triggers protective antibodies and immune cells. Participants received a single dose, and researchers measured antibody levels, B cells, and T cell responses. The goal is to understand the vaccine's immune effects and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vaxchora (live attenuated oral cholera vaccine)

What this could lead to

If successful, this study could confirm that Vaxchora produces strong immune memory, supporting its use for cholera prevention.

What could go wrong

This is a small, early-phase study with only 34 healthy adults, so results may not apply to broader populations. The vaccine may not provide long-lasting protection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infectious disease cholera prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Hope Clinic of Emory University

    Atlanta, Georgia, 30030, United States