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Cholera vaccine ring strategy tested in bangladesh hotspots

NCT ID NCT07685574

Recruiting now Prevention Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests a targeted approach to stop cholera spread in Dhaka, Bangladesh. When someone tests positive for cholera, their household and nearby neighbors (within about 20–40 meters) are offered an oral cholera vaccine. The goal is to see if this ring vaccination reduces the number of new cholera cases over three years. Around 68,400 people are expected to take part, and researchers will track infections through hospital surveillance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Oral cholera vaccine (Cholvax)
What this could lead to
If effective, this targeted vaccination strategy could help control cholera outbreaks in high-risk urban areas, reducing the spread of disease.
What could go wrong
The study is observational in design, not a randomized controlled trial, so results may be influenced by other factors. Vaccine effectiveness may vary by dose and community compliance.

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Conditions

The condition(s) this trial relates to.

cholera

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOLERA METHODOLOGY STUDY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • International Centre for Diarrhoeal Diseases Research, Bangladesh (icddr,b)

    RECRUITING

    Dhaka, 1212, Bangladesh

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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