Natural materials may speed gum graft recovery

NCT ID NCT07072546

Completed Symptom relief Sponsor: Biruni University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether applying chitosan (a natural substance from shellfish) and i-PRF (a concentrate from the patient's own blood) to the wound site can improve healing after a gum graft. Sixty-eight people received one of three treatments: a standard gelatin sponge, chitosan alone, or chitosan with i-PRF. Researchers measured pain, bleeding, and how quickly the wound healed over two months. The goal is to find a way to make recovery more comfortable and faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: chitosan and injectable platelet-rich fibrin (i-PRF)
What this could lead to: If it works, this could lead to a simple, natural way to speed up healing and reduce pain after gum graft surgery.
What could go wrong: This is a small, completed study with 68 people. The results may not apply to everyone, and the benefits over standard care might be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHITOSAN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHITOSAN FREE GINGIVAL GRAFT I-PRF WOUND HEALING

Contacts and locations

Locations

Biruni University

Istanbul, Turkey (Türkiye)
Cukurova University

Adana, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.