Natural materials may speed gum graft recovery

NCT ID NCT07072546

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether applying chitosan (a natural substance from shellfish) and i-PRF (a concentrate from the patient's own blood) to the wound site can improve healing after a gum graft. Sixty-eight people received one of three treatments: a standard gelatin sponge, chitosan alone, or chitosan with i-PRF. Researchers measured pain, bleeding, and how quickly the wound healed over two months. The goal is to find a way to make recovery more comfortable and faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

chitosan and injectable platelet-rich fibrin (i-PRF)

What this could lead to

If it works, this could lead to a simple, natural way to speed up healing and reduce pain after gum graft surgery.

What could go wrong

This is a small, completed study with 68 people. The results may not apply to everyone, and the benefits over standard care might be small.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Biruni University

    Istanbul, Turkey (Türkiye)

  • Cukurova University

    Adana, Turkey (Türkiye)