Massive study aims to unlock genetic secrets of childhood hormone disorders

NCT ID NCT02769975

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 5 times

Summary

This study enrolls up to 15,000 children with known or suspected endocrine or metabolic disorders, along with their family members. Researchers will collect medical records, blood, saliva, and other samples to identify genetic changes linked to these conditions. The goal is to better understand how these disorders are inherited and to improve future diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could uncover genetic roots of rare endocrine and metabolic disorders, pointing toward better diagnostic tests and potential treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not directly benefit participants, and genetic findings may take years to translate into therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.