Could a concentrated dose of your own healing factors ease knee arthritis?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years, with no gender restrictions; * Patients diagnosed with knee osteoarthritis according to the "Chinese Guidelines for the Diagnosis and Treatment of Osteoarthritis (2024 Edition)" by the Chinese Osteoarthritis Diagnosis and Treatment Guidelines Expert Group; * Radiographic evidence of knee osteoarthritis with Kellgren-Lawrence grading of II to IV; * Visual Analog Scale (VAS) pain score ≥ 4 (moderate or higher pain) and WOMAC score ≥ 24; * For participants with eligible bilateral knee osteoarthritis, the more severely affected knee will be treated, while the other knee will not be intervened during the study period. If the severity is equal on both sides, the left knee will be selected for intervention; * The patient or their legal guardian is able to understand the purpose of the study and provide informed consent. Exclusion Criteria: * Patients with a confirmed diagnosis of other inflammatory diseases of the knee joint, such as rheumatoid arthritis, psoriatic arthritis, or gouty arthritis; Patients with a confirmed diagnosis of bleeding disorders (e.g., allergic purpura, hemophilia, idiopathic thrombocytopenic purpura), hematologic malignancies (e.g., leukemia), or those with unconfirmed bleeding disorders but coagulation dysfunction (coagulation parameters PT, APTT, INR \> 1.5 times the upper limit of normal); * Patients who have undergone or are planned to undergo knee osteoarthritis surgery within the past 6 months or during the trial period; * Patients with local infections at the injection site (e.g., septic arthritis, tuberculous arthritis, or local soft tissue infections) or severe systemic infections (e.g., sepsis); * Patients with untreated malignant diseases such as malignancies, which may interfere with the safety and efficacy assessments of the study and affect the patient's participation in the study; * Patients with severe hepatic or renal dysfunction \[hepatic function indicators alanine aminotransferase (ALT), aspartate aminotransferase (AST) \> 2 times the upper limit of normal; renal function indicators serum creatinine (Cr), blood urea nitrogen (BUN) \> 2 times the upper limit of normal\]; * Patients with hemoglobin \< 10 g/dL or platelet count \< 125 × 10\^9/L; * Patients who have used any Chinese or Western medications or therapies for the treatment of knee osteoarthritis within 1 week prior to randomization; * Patients who have received intra-articular injections or related drug therapies within the past 3 months; * Women who are planning a pregnancy, breastfeeding, or pregnant during the entire clinical study period; * Patients who have participated in other interventional drug or medical device clinical trials within 1 month prior to enrollment; * Other situations where the investigator deems the patient unsuitable for participation in this study.