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Could a concentrated dose of your own healing factors ease knee arthritis?

NCT ID NCT06869200

Completed Disease control Sponsor: Guangdong Hongzhi Health Technology Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial investigates whether a concentrated growth factor (CGF) preparation, made from a patient's own blood, can reduce pain and improve function in people with knee osteoarthritis. Participants receive three weekly injections of either CGF or standard platelet-rich plasma (PRP) into the knee. The study compares the two treatments to see if CGF offers better symptom relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Concentrated Growth Factor (CGF) from the patient's own blood
What this could lead to
If it works, this could offer a more effective, natural treatment option for knee osteoarthritis pain and stiffness, potentially delaying the need for surgery.
What could go wrong
This is a relatively small, early-stage trial, and the treatment may not prove superior to existing options like PRP. There is also a risk of injection-related side effects such as pain or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KNEE OSTEOARTHRITIS

Contacts and locations

Locations

  • Nanfang Hospital,

    Guangzhou, Guangdong, 510515, China

  • Shantou Central Hospital

    Shantou, Guangdong, 515000, China

  • The Third Affiliated Hospital,Sun Yat-Sen University.

    Guangdong, Guangzhou, 510000, China

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