Neck flap may cut fistula risk after throat cancer surgery

NCT ID NCT07241611

Completed Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether placing a flap of neck tissue over the closure line after total larynx removal (laryngectomy) could lower the chance of a pharyngocutaneous fistula—an abnormal opening that can leak saliva and delay healing. Fifty patients with advanced laryngeal cancer took part. The goal was to see if this simple surgical addition improves healing and reduces complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cervical fascia flap (surgical procedure)
What this could lead to: If successful, this technique could reduce a common complication after larynx removal surgery, improving recovery and quality of life.
What could go wrong: This is a small, single-center study with 50 patients. Results may not apply to everyone, and the procedure itself carries surgical risks.

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Conditions

The condition(s) this trial relates to.

laryngeal carcinoma laryngeal neoplasm larynx cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALIGNANT TUMOR OF THE LARYNX

Contacts and locations

Locations

Faculty of Medicine, Mansoura University

Al Mansurah, Dakahlia Governorate, 35511, Egypt

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