New surgical trick may prevent dangerous leaks after throat cancer surgery

NCT ID NCT06287034

Recruiting now Disease control Sponsor: Regina Elena Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether using a piece of the patient's own tissue (a flap) to reinforce the closure after removing the voice box can reduce the risk of a throat leak (fistula). About 102 people whose throat cancer has returned after radiation or chemoradiation will be randomly assigned to standard closure or closure with a flap. The goal is to see which approach leads to fewer leaks and better quality of life.

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Conditions

The condition(s) this trial relates to.

laryngeal carcinoma laryngeal neoplasm laryngeal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LARYNX CARCINOMA

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

"Regina Elena" National Cancer Institute
RECRUITING

Rome, Rome, 00144, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••