New CT scanner could sharpen view of throat cancer
NCT ID NCT07603167
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new type of CT scan, called Photon-Counting CT, to see if it can more accurately show how far laryngeal cancer has spread. Sixty adults with laryngeal cancer will get this scan while making a sound, which may help separate normal tissues from tumor. The goal is to improve treatment planning and avoid both undertreatment and overly aggressive surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Photon-Counting CT scan
- What this could lead to
- If successful, this could provide a more accurate, non-invasive way to stage laryngeal cancer, potentially reducing unnecessary surgeries or missed tumor spread.
- What could go wrong
- This is a small pilot study (60 people) testing a new imaging technique. It may not prove better than current methods, and results may not apply to all patients or hospitals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of sixty patients, with biopsy-proven laryngeal squamous cell carcinoma will be enrolled in the study.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1\. SELECTION CRITERIA Inclusion Criteria * Adults (≥18 years) * Biopsy-proven laryngeal cancer squamous cell carcinoma * Candidate for surgical staging able to undergo PCCT Exclusion criteria * Renal failure * Allergy to contrast medium * Refusal of informed consent * Lack of histopathologic confirmation * Histopathologic diagnosis of non laryngeal tumors * Poor image quality due to severe artifacts
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Humanitas Research Hospital
Rozzano, 20089, Italy
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