Engineered immune cells take on tough leukemia

NCT ID NCT02146924

First seen Jan 05, 2026 · Last updated May 12, 2026 · Updated 17 times

Summary

This early-stage study tests a new cellular therapy for adults with high-risk acute lymphoblastic leukemia (ALL) that has come back or not responded to treatment. Researchers take a patient's own white blood cells, add a gene to help them recognize and attack cancer cells, and infuse them back after chemotherapy. The main goals are to find the safest dose and understand side effects, while also checking if the treatment can reduce or eliminate leukemia.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.