REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Clinical trials for REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA explained in plain language.
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Modified immune cells battle childhood leukemia in new trial
Disease control Recruiting nowThis study is testing a treatment called CAR T-cell therapy for children and young adults (up to age 21) whose CD19-positive leukemia has come back or hasn't responded to other treatments. Doctors collect a patient's own immune cells, modify them in a lab to better target cancer,…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Six-Drug attack on tough blood cancers shows promise
Disease control Recruiting nowThis study is testing a combination of six chemotherapy drugs for people whose acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma has come back or hasn't responded to previous treatments. The goal is to see if this intensive combination is safe and can effectively contr…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New immune cell therapy targets aggressive blood cancers in kids and adults
Disease control Recruiting nowThis study is testing a new type of personalized immune cell therapy called CD7 CAR T-cells for patients with T-cell blood cancers that have returned or not responded to other treatments. The therapy involves collecting a patient's own immune cells or using donor cells, modifying…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Beijing GoBroad Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New 'Living Drug' trial targets aggressive blood cancers in kids and adults
Disease control Recruiting nowThis study is testing a new type of personalized cell therapy called CD5 CAR-T for people with T-cell cancers that have come back or not responded to other treatments. Doctors will modify a patient's own immune cells (or cells from a donor) to better target and fight the cancer. …
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Beijing GoBroad Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Supercharged immune cells: new hope for tough leukemia cases
Disease control Recruiting nowThis early-phase study is testing the safety of a new type of CAR T-cell therapy for adults and teenagers (12+) with acute lymphoblastic leukemia (ALL) that has come back or not responded to other treatments. Doctors take a patient's own immune cells, modify them in a lab to bett…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New Triple-Target immune therapy enters human trials for aggressive blood cancers
Disease control Recruiting nowThis early-stage trial is testing the safety and best dose of a new type of CAR-T cell therapy designed to attack three different proteins (CD19, CD20, and CD22) found on cancer cells. It is for adults with certain aggressive blood cancers like non-Hodgkin lymphoma, acute lymphob…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New 'Smart Bomb' radiation therapy tested for Tough-to-Treat leukemias
Disease control Recruiting nowThis study is testing a new experimental drug that delivers radiation directly to cancer cells in patients with high-risk blood cancers like acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The goal is to find the safest and most effective dose of this targete…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Targeted radiation zaps blood cancer cells before transplant
Disease control Recruiting nowThis study is testing a new treatment for aggressive blood cancers (like leukemia or MDS) that have come back or are not responding to standard therapies. The treatment involves a radioactive antibody designed to seek out and destroy cancer cells, followed by a stem cell transpla…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Custom immune cells fight blood cancers after transplant
Disease control Recruiting nowThis study tests a personalized immune cell therapy for patients with blood cancers like leukemia, lymphoma, and myeloma. After receiving chemotherapy and a cord blood transplant, patients get infusions of natural killer (NK) cells—immune cells that may kill remaining cancer cell…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Engineered immune cells take aim at tough leukemia
Disease control Recruiting nowThis early-stage trial is testing a new version of CAR T-cell therapy for adults with a type of blood cancer called B-cell acute lymphoblastic leukemia (ALL) that has come back or not responded to other treatments. Doctors take a patient's own immune cells, modify them in a lab t…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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New combo attack on tough leukemia shows promise
Disease control Recruiting nowThis study is testing a new combination of drugs for adults with a specific, aggressive type of leukemia (Philadelphia chromosome-positive ALL) that has come back or hasn't responded to other treatments. The treatment combines an immunotherapy drug that helps the immune system fi…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 17, 2026 13:08 UTC
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New pill tested for Tough-to-Treat blood cancers
Disease control Recruiting nowThis study is testing an oral drug called ONC201, alone or with another drug, for adults with advanced blood cancers that have returned or are not responding to standard treatments. The main goals are to find the safest and most effective dose and to see if the treatment can help…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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Engineered immune cells target Leukemia's return
Disease control Recruiting nowThis early-stage trial is testing a new cell therapy for children and adults whose leukemia has come back or persists after a donor stem cell transplant. Doctors take immune cells (T cells) from the original donor, genetically modify them to better recognize and attack the patien…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Mar 05, 2026 13:59 UTC
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New hope for incurable blood cancers: experimental CAR-T therapy enters trial
Disease control Recruiting nowThis study is testing a new type of personalized immune cell therapy, called CD5-CAR T cells, for people with aggressive T-cell blood cancers that have come back or not responded to standard treatments. The main goals are to find a safe and effective dose and to see if the therap…
Matched conditions: REFRACTORY ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Beijing GoBroad Hospital • Aim: Disease control
Last updated Mar 02, 2026 15:28 UTC