New hope for bile duct cancer: Four-Drug cocktail trial launches

NCT ID NCT05849480

First seen Jan 27, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This study tests a new drug (CDX-1140) plus three standard cancer drugs (capecitabine, oxaliplatin, and Keytruda) in people with advanced bile duct cancer that has stopped responding to treatment. About 60 adults will receive the drugs in 21-day cycles for up to 2 years, with follow-up for 3 more years. The goal is to find a safe dose and see if the combination can shrink tumors or delay cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.