Engineered immune cells take on deadly brain cancer in early trial

NCT ID NCT05353530

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 23 times

Summary

This early-phase study tests a personalized cell therapy for adults with glioblastoma and children with high-grade gliomas. The treatment uses a patient's own immune cells, modified to target a protein called CD70 on tumor cells and to better navigate to the brain. The main goals are to see if the therapy is safe and feasible to deliver.

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Contacts and locations

Locations

  • University of Florida Health

    Gainesville, Florida, 32608, United States

Conditions

Explore the condition pages connected to this study.