Cord blood cells engineered to fight lung cancer in early trial

NCT ID NCT05334329

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 30 times

Summary

This early-phase study tests a new treatment for people with advanced non-small cell lung cancer that no longer responds to standard immunotherapy. The treatment uses immune cells from donated umbilical cord blood that are genetically modified to better recognize and attack cancer cells. Some participants also receive an additional immunotherapy drug (atezolizumab). The main goal is to check safety and find the best dose in a small group of 6 adults.

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Contacts and locations

Locations

  • Chao Family Comprehensive Cancer Center University of California, Irvine

    Orange, California, 92868, United States

Conditions

Explore the condition pages connected to this study.