STAGE IIIB LUNG CANCER AJCC V8
Clinical trials for STAGE IIIB LUNG CANCER AJCC V8 explained in plain language.
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New drug combo aims to extend life in lung cancer patients
Disease control Recruiting nowThis phase 3 trial compares a two-drug combination (osimertinib plus bevacizumab) against osimertinib alone as the first treatment for people with advanced EGFR-mutant non-small cell lung cancer. The goal is to see if adding bevacizumab helps control the cancer longer and improve…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 16, 2026 20:33 UTC
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New combo therapy aims to control advanced lung cancer after standard treatment fails
Disease control Recruiting nowThis study tests whether adding local treatments like surgery or radiation to the immunotherapy drug durvalumab can help control stage III non-small cell lung cancer that has started to grow again after chemoradiation and durvalumab. About 51 adults will receive this combination.…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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Custom-Made vaccine plus immunotherapy shows promise for advanced cancers
Disease control Recruiting nowThis study tests a personalized vaccine made from a patient's own tumor proteins, given alone or with the immunotherapy drug pembrolizumab, for people with advanced solid tumors (like breast, lung, or skin cancer). The goal is to see if the combination is safe and helps control t…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 15, 2026 19:09 UTC
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Immunotherapy boost after lung cancer surgery shows promise in major trial
Disease control Recruiting nowThis study is for people with stage II to IIIB non-small cell lung cancer that has been surgically removed. It tests whether adding the immunotherapy drug pembrolizumab to standard chemotherapy can help keep the cancer from coming back and extend survival. About 1,210 participant…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 18:54 UTC
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Simple breathing workouts before lung surgery may cut pneumonia risk, study says
Disease control Recruiting nowThis study tests whether doing special breathing exercises before lung cancer surgery can help prevent serious lung problems like pneumonia after the operation. About 220 people with stage I-IIIB lung cancer will either do these exercises or receive usual care. The goal is to see…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jun 12, 2026 12:03 UTC
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Could a drug after surgery keep lung cancer from coming back?
Disease control Recruiting nowThis study tests whether the immunotherapy drug durvalumab, given after surgery, can help prevent early-stage non-small cell lung cancer from returning. About 306 people who have had their lung cancer completely removed will either receive durvalumab or be watched closely (standa…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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New trial aims to find best treatment for older lung cancer patients
Disease control Recruiting nowThis study tests whether adding chemotherapy to immunotherapy (pembrolizumab) helps older adults (70+) with advanced non-small cell lung cancer live longer compared to immunotherapy alone. The trial enrolls 304 participants with stage IIIB-IV cancer and a specific PD-L1 level. Th…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 09, 2026 12:09 UTC
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Lung cancer trial tests best time for treatment: before and after surgery or just after?
Disease control Recruiting nowThis study compares two standard approaches for people with stage II-IIIB non-small cell lung cancer that can be removed with surgery. One group gets chemotherapy and immunotherapy both before and after surgery, while the other gets the same treatments only after surgery. The goa…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 02, 2026 11:57 UTC
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Double immune punch before lung cancer surgery shows promise
Disease control Recruiting nowThis study tests whether giving a combination of two immunotherapy drugs (cemiplimab and fianlimab) before surgery can kill more tumor cells in people with stage IB to IIIB non-small cell lung cancer. About 60 adults will receive the drug combination before their tumor is removed…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 01, 2026 17:54 UTC
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Can a drug stop lung cancer before it starts? new trial aims to find out
Prevention Recruiting nowThis study tests whether the drug canakinumab can prevent lung cancer in 50 people who have suspicious lung nodules that haven't gone away. Participants receive the drug and are monitored for nodule shrinkage and cancer development. The goal is to see if this approach can stop lu…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Jun 11, 2026 12:12 UTC
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Yoga may ease cancer treatment side effects for patients and families
Symptom relief Recruiting nowThis study tests whether a special yoga program can improve physical function, fatigue, sleep, and quality of life for people with lung or esophageal cancer who are getting radiation therapy, as well as for their family caregivers. About 400 patient-caregiver pairs will take part…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 15, 2026 19:09 UTC
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Could a poop transplant fix cancer treatment side effects?
Knowledge-focused Recruiting nowThis study looks at how the bacteria in your gut might cause stomach issues like diarrhea and colitis when you take certain cancer drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung cancer, or g…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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Can personalized chemoradiation protect lung cancer Patients' hearts?
Knowledge-focused Recruiting nowThis study looks at how chemoradiation for locally advanced lung cancer affects the heart. Researchers will track heart injury and fitness in 100 patients receiving treatment tailored to their individual risk. The goal is to learn if personalized planning can reduce heart problem…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:54 UTC
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Blood tests may guide better lung cancer treatment choices
Knowledge-focused Recruiting nowThis study looks at blood and tissue samples from people with advanced non-small cell lung cancer to find markers that predict how well immunotherapy works. The goal is to use these markers to choose the best second-line treatment if the first one stops working. About 535 partici…
Matched conditions: STAGE IIIB LUNG CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:08 UTC