Engineered immune cells take on resistant prostate cancer in first human test

NCT ID NCT03089203

First seen Feb 23, 2026 · Last updated Apr 28, 2026 · Updated 10 times

Summary

This early-phase study tests a new treatment for men with advanced prostate cancer that no longer responds to hormone therapy. The treatment uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells while resisting signals that normally shut them down. The main goal is to see if this approach is safe and possible to deliver, with 23 participants enrolled.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.