Can a scan predict radiation harm to heart and lungs?

NCT ID NCT04901884

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking for early signs of heart and lung damage in people receiving radiation for chest cancers. Researchers will use PET/MR scans and blood tests before and after treatment to see if they can predict who will develop problems like pulmonary hypertension. The goal is to find better ways to monitor and eventually prevent these side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-FDG (a radioactive tracer used in PET scans)

What this could lead to

If successful, this could help doctors identify patients at risk of heart or lung damage from chest radiation earlier, potentially guiding personalized follow-up care.

What could go wrong

This is a small, early exploratory study with only 40 participants. It is not testing a treatment, so it may not lead to any direct benefit for patients. The markers studied may not prove reliable in larger groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary hypertension thoracic cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact