New drug duo aims to stop kidney rejection in its tracks

NCT ID NCT06918990

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This early-stage study tests two drugs, carfilzomib and belatacept, in 25 kidney transplant recipients whose bodies are attacking the new organ. The goal is to see if the combination is safe and can reduce harmful antibodies or improve kidney function over a year. Participants will continue taking standard anti-rejection medications throughout the study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University

    NOT_YET_RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mayo Clinic Arizona

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern University, Feinberg School of Medicine

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Medical Center (Site #: 71123)

    NOT_YET_RECRUITING

    Los Angeles, California, 90024, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama Medical Center

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Cincinnati

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45267, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Wisconsin - Madison

    NOT_YET_RECRUITING

    Madison, Wisconsin, 53726, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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