New hope for advanced breast cancer: drug combo targets resistant tumors
NCT ID NCT06764186
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a combination of two drugs, capivasertib and fulvestrant, in 101 people with a specific type of advanced breast cancer (HR+/HER2-) that has stopped responding to hormone therapy and a CDK4/6 inhibitor. The goal is to see how long it takes before the next cancer treatment is needed, while also checking safety. Participants must have a specific genetic change (PIK3CA/AKT1/PTEN) in their tumor.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Alicante, 03010, Spain
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Research Site
Barcelona, 08003, Spain
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Research Site
Barcelona, 08035, Spain
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Research Site
Barcelona, 08036, Spain
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Research Site
Bilbao (Vizcaya), 48013, Spain
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Research Site
Córdoba, 14004, Spain
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Research Site
Donostia / San Sebastian, 20014, Spain
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Research Site
El Palmar, 30120, Spain
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Research Site
Girona, 17007, Spain
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Research Site
Madrid, 28041, Spain
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Research Site
Oviedo, 33011, Spain
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Research Site
Palma deMallorca, 07010, Spain
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Research Site
Salamanca, 37007, Spain
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Research Site
Santander, 39008, Spain
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Research Site
Seville, 41073, Spain
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Research Site
Valencia, 46026, Spain
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Research Site
Zaragoza, 50009, Spain