New hope for advanced breast cancer: drug combo targets resistant tumors
NCT ID NCT06764186
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times
Summary
This study tests a combination of two drugs, capivasertib and fulvestrant, in people with a certain type of advanced breast cancer (HR+/HER2-) that has stopped responding to standard hormone therapy and a CDK4/6 inhibitor. The goal is to see how well the combo works in real-world settings in Spain. About 101 participants with specific genetic changes (PIK3CA/AKT1/PTEN) will be followed to measure how long until they need another cancer treatment.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Research Site
Alicante, 03010, Spain
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Research Site
Barcelona, 08003, Spain
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Research Site
Barcelona, 08035, Spain
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Research Site
Barcelona, 08036, Spain
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Research Site
Bilbao (Vizcaya), 48013, Spain
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Research Site
Córdoba, 14004, Spain
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Research Site
Donostia / San Sebastian, 20014, Spain
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Research Site
El Palmar, 30120, Spain
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Research Site
Girona, 17007, Spain
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Research Site
Madrid, 28041, Spain
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Research Site
Oviedo, 33011, Spain
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Research Site
Palma deMallorca, 07010, Spain
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Research Site
Salamanca, 37007, Spain
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Research Site
Santander, 39008, Spain
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Research Site
Seville, 41073, Spain
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Research Site
Valencia, 46026, Spain
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Research Site
Zaragoza, 50009, Spain
Conditions
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