New hope for Drug-Resistant breast cancer: phase 3 trial launches

NCT ID NCT07354022

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial is testing whether a new drug called HRS-8080, combined with dalpiciclib, works better than the standard treatment (fulvestrant plus dalpiciclib) for people with advanced breast cancer that has become resistant to hormone therapy. About 912 women aged 18-75 with locally advanced or metastatic breast cancer will take part. The main goal is to see how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HRS-8080 tablet combined with dalpiciclib

What this could lead to

If it works, this could offer a new treatment option for advanced breast cancer that has stopped responding to standard hormone therapy.

What could go wrong

This is a large phase 3 trial, but it's still experimental. The new drug may not improve outcomes or could cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chinese PLA General Hospital Fifth Medical Center

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

    Contact