Simple gloves and socks may shield breast cancer patients from chemo nerve pain

NCT ID NCT07638774

Recruiting now Symptom relief Sponsor: Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether wearing compression or ice gloves and socks can reduce nerve damage caused by the chemotherapy drug UTD1 in women with advanced breast cancer. 324 participants will be randomly assigned to wear nothing, compression gloves/socks, or ice gloves/socks during treatment. The goal is to see if these simple devices lower the risk of painful or numb hands and feet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: compression glove/sock and ice glove/sock
What this could lead to: If it works, this could offer a simple, low-cost way to prevent chemotherapy-induced nerve damage, improving quality of life for breast cancer patients.
What could go wrong: This is a phase 3 trial, but the intervention is a device, not a drug, so the effect may be modest. It may not work for everyone, and results may not apply to other chemotherapy drugs.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED OR METASTATIC BREAST CANCER

Contacts and locations

Locations

Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, China

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