Promising drug combo aims to control advanced breast cancer when standard therapy fails

NCT ID NCT07222215

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a combination of two drugs (elacestrant and capecitabine) to capecitabine alone in people with advanced estrogen receptor-positive breast cancer that no longer responds to CDK 4/6 inhibitors. About 297 participants will be randomly assigned to one of the two treatment groups. The goal is to see if the combination helps keep the cancer from growing longer than the single drug.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

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Other studies related to the condition(s) this trial covers.