ESR1 GENE MUTATION
Clinical trials for ESR1 GENE MUTATION explained in plain language.
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New hope for Tough-to-Treat breast cancer: major trial tests powerful drug duo
Disease control Recruiting nowThis study is testing whether adding the drug everolimus to a newer hormone therapy (elacestrant) works better for controlling advanced breast cancer than the hormone therapy alone. It is for people whose cancer has a specific mutation (ESR1) and has continued to grow despite sta…
Matched conditions: ESR1 GENE MUTATION
Phase: PHASE3 • Sponsor: MedSIR • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Special scan could Fine-Tune breast cancer drug dose
Disease control Recruiting nowThis small, early-phase study is testing a new approach for patients whose metastatic breast cancer has become resistant to standard hormone therapy due to a specific gene change (ESR1 mutation). Researchers will use a special imaging scan (FES-PET/CT) to see how well the drug ta…
Matched conditions: ESR1 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New hope for Tough-to-Treat breast cancer: two drugs vs. one
Disease control Recruiting nowThis study is testing if combining two drugs, capecitabine and elacestrant, works better than just capecitabine alone for people with advanced, hormone-sensitive breast cancer. It's for patients whose cancer has stopped responding to a common class of prior medications. The main …
Matched conditions: ESR1 GENE MUTATION
Phase: PHASE2 • Sponsor: Kristina A. Fanucci • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC