VA launches major trial of THC and CBD for Veterans' nerve pain
NCT ID NCT05351801
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This phase 2 trial is testing whether cannabis-based medicines—THC, CBD, or a combination—can safely reduce chronic nerve pain in Veterans. 320 participants will receive one of these treatments or a placebo for six weeks. The goal is to see if these options offer better pain relief than current treatments, which often fall short.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Providence VA Medical Center, Providence, RI
RECRUITINGProvidence, Rhode Island, 02908-4734, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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South Texas Health Care System, San Antonio, TX
RECRUITINGSan Antonio, Texas, 78229-4404, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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VA Connecticut Healthcare System West Haven Campus, West Haven, CT
RECRUITINGWest Haven, Connecticut, 06516-2770, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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VA Greater Los Angeles Healthcare System, West Los Angeles, CA
ACTIVE_NOT_RECRUITINGWest Los Angeles, California, 90073-1003, United States
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VA Puget Sound Health Care System Seattle Division, Seattle, WA
TERMINATEDSeattle, Washington, 98108-1532, United States
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VA San Diego Healthcare System, San Diego, CA
RECRUITINGSan Diego, California, 92161-0002, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
THC (Syndros), CBD (Epidiolex), and THC+CBD (Nabiximols)
What this could lead to
If successful, this trial could provide evidence that cannabis-based medicines are a safe and effective option for managing chronic neuropathic pain, especially for Veterans.
What could go wrong
This is a mid-stage trial with 320 participants, so results are not definitive. The effects may be modest, and side effects like dizziness or drowsiness are possible. It also focuses on Veterans, so findings may not apply to everyone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.