New hope for patients whose cancer stopped responding to standard immunotherapy

NCT ID NCT03228667

Summary

This study is testing a new combination of immune-boosting drugs for people with advanced cancers whose disease has progressed after treatment with standard immunotherapies like pembrolizumab or nivolumab. It aims to see if adding a drug called NAI to other treatments can help shrink tumors and extend survival. The trial is for adults with specific advanced cancers, including lung cancer, who meet strict eligibility criteria based on their prior treatment history and current health.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alaska Clinical Research Center

    Anchorage, Alaska, 99530, United States

  • Baptist Health - Lexington

    Lexington, Kentucky, 40503, United States

  • Baptist Health- Louisville

    Louisville, Kentucky, 40207, United States

  • Bon Secours Richmond

    Richmond, Virginia, 23114, United States

  • Chan Soon-Shiong Institute for Medicine

    El Segundo, California, 90245, United States

  • Cleveland Clinic - Main Site

    Cleveland, Ohio, 44195, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Desert Hematology Oncology Medical Group, Inc.

    Rancho Mirage, California, 92270, United States

  • Genesis Cancer Center

    Hot Springs, Arkansas, 71913, United States

  • Gettysburg/Hanover Cancer Centers

    Gettysburg, Pennsylvania, 17325, United States

  • Glendale Adventist Medical Center

    Glendale, California, 91206, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Horizon Oncology Associates

    Lafayette, Indiana, 47905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Memorial Healthcare System

    Hollywood, Florida, 33021, United States

  • MemorialCare Health System

    Fountain Valley, California, 37846, United States

  • Mercy Clinic Cancer & Hematology - Chub O'Reilly Cancer Center

    Springfield, Missouri, 65804, United States

  • Mercy Clinic Oklahoma City

    Oklahoma City, Oklahoma, 73120, United States

  • Mercy Research Joplin

    Joplin, Missouri, 64804, United States

  • Miami Cancer Institute (Baptist Health South Florida)

    Miami, Florida, 33176, United States

  • Oncology Consultants of Houston

    Houston, Texas, 77024, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • Sanford Clinical Research

    Sioux Falls, South Dakota, 57104, United States

  • Spartanburg Medical Center

    Spartanburg, South Carolina, 29303, United States

  • St. Francis Cancer Center/Bon Secours St. Francis Health System

    Greenville, South Carolina, 29607, United States

  • St. Vincent Frontier Cancer Center (SCL)

    Billings, Montana, 59102, United States

  • University of Iowa Holden Comprehensive Cancer Center

    Iowa City, Iowa, 52242, United States

  • University of Miami

    Miami, Florida, 33180, United States

  • University of Minnesota - Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

  • University of Rochester

    Rochester, New York, 14642, United States

  • University of Southern California Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Tennessee Medical Center

    Knoxville, Tennessee, 37920, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.