Can a gentle brain zap make counseling more effective for cannabis users?
NCT ID NCT07787572
First seen Aug 26, 2026 · Last updated Aug 28, 2026 · Updated 2 times
Summary
This trial explores whether adding a gentle brain stimulation technique called transcranial alternating current stimulation (tACS) to a brief counseling session can help adults with cannabis use disorder. The counseling, known as motivational interviewing, helps people talk through their reasons for changing their cannabis use. Researchers will compare active tACS to a placebo version, measuring what participants say during the session, brain activity afterward, and cannabis use over the following month. The goal is to see if this combination can strengthen the counseling's impact.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial alternating current stimulation (tACS) — a device that delivers a weak electrical current to the brain via scalp electrodes during a counseling session
- What this could lead to
- If it works, this could point toward a way to make brief counseling more effective for people trying to cut back on cannabis, potentially improving treatment outcomes.
- What could go wrong
- This is an early-stage trial with a modest number of participants, so results may not be conclusive. The stimulation is weak and short, and its effect on real-world cannabis use is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 82 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * self-identification as having problematic cannabis use * age 21-65 years * SCID-5-RV module E indicating current cannabis use disorder Exclusion Criteria: * currently engaged in treatment for any substance use disorder (SUD) * receiving treatment for any SUD within the prior 30 days * history of brain injury or major neurological diagnosis, vascular/neurodegenerative disorder, or complex primary headache disorder * evidence of current psychosis * past-year substance use disorder other than cannabis, alcohol, or nicotine * positive urine drug screen for any illicit drug other than cannabis * current or recent (past-month) medically significant withdrawal * MRI/tACS contraindications, including pregnancy * impaired hearing (psychotherapy using American Sign Language is not possible within the scope of this study) * insufficient corrected visual acuity to complete the assessment instruments * unable to read/speak English fluently * unable to provide valid informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Mind Research Network
Albuquerque, New Mexico, 87106, United States
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- Brain zaps could curb cannabis cravings in youth