Toothache relief showdown: calcium hydroxide vs tobradex
NCT ID NCT07332936
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two medications placed inside the tooth after an emergency root canal to see which one reduces pain better. 43 adults with severe tooth pain (pulpitis) received either calcium hydroxide or Tobradex (an antibiotic-steroid combo). Pain levels were measured before treatment and at 24 and 48 hours after. The goal was to find a faster way to ease post-procedure pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Calcium hydroxide or tobramycin-dexamethasone (Tobradex) placed inside the tooth after cleaning
What this could lead to
If Tobradex works better, dentists may have a new option to reduce pain quickly after emergency root canals.
What could go wrong
This was a small, completed trial with only 43 participants, so results may not apply to everyone. Pain relief differences may be small.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Dental Medicine, Umm Al-Qura University
Mecca, Saudi Arabia