Toothache relief showdown: calcium hydroxide vs tobradex
NCT ID NCT07332936
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two medications placed inside the tooth after an emergency root canal to see which one reduces pain better. 43 adults with severe tooth pain (pulpitis) received either calcium hydroxide or Tobradex (an antibiotic-steroid combo). Pain levels were measured before treatment and at 24 and 48 hours after. The goal was to find a faster way to ease post-procedure pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Calcium hydroxide or tobramycin-dexamethasone (Tobradex) placed inside the tooth after cleaning
- What this could lead to
- If Tobradex works better, dentists may have a new option to reduce pain quickly after emergency root canals.
- What could go wrong
- This was a small, completed trial with only 43 participants, so results may not apply to everyone. Pain relief differences may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTOPERATIVE ENDODONTIC PAIN FOLLOWING EMERGENCY ROOT CANAL TREATMENT are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dental Medicine, Umm Al-Qura University
Mecca, Saudi Arabia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a gentler root canal tool ease post-treatment pain?
- Could a simple injection make root canals less painful?
- Could a simple steroid shot make root canals less painful?
- Could a cold rinse during root canals ease Post-Procedure pain?
- Chill after the drill: could cold saline soothe root canal pain?
- Could a simple device make root canals less painful?