Can a COPD inhaler also help your heart?

NCT ID NCT07073950

First seen Jun 26, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study tests a triple-combination inhaler (budesonide, glycopyrronium, and formoterol) against a placebo in 56 people with COPD and lung hyperinflation. The goal is to see if the inhaler improves both lung function and heart function, measured by MRI. Participants will receive the inhaler or placebo in a crossover design, meaning everyone gets both treatments at different times.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Budesonide/Glycopyrronium/Formoterol fumarate (a triple-combination inhaler)
What this could lead to
If it works, this could show that the inhaler improves both lung and heart function in people with COPD and hyperinflation, potentially leading to better management of the disease.
What could go wrong
This is a small, early-phase 4 trial with only 56 participants, so results may not apply to everyone. The study is also short-term, so long-term benefits or risks are unknown.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    RECRUITING

    Ahrensburg, 22926, Germany

  • Research Site

    RECRUITING

    Berlin, 14050, Germany

  • Research Site

    RECRUITING

    Frankfurt, 60596, Germany

  • Research Site

    RECRUITING

    Hanover, 30625, Germany

  • Research Site

    WITHDRAWN

    Harefield, UB9 6JH, United Kingdom

  • Research Site

    RECRUITING

    London, W1T 6AH, United Kingdom

  • Research Site

    RECRUITING

    Manchester, M23 9QZ, United Kingdom

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