Could a diabetes drug ease chest pain in women with hidden heart disease?
NCT ID NCT06600178
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a drug called Brezavvy (an SGLT2 inhibitor) can improve blood flow in the tiny vessels of the heart and reduce chest pain in women who have angina but no blocked major arteries. 150 women will take either the drug or a placebo for 12 weeks and undergo heart scans and questionnaires. The goal is to see if this treatment can help manage a condition that often goes undiagnosed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Brezavvy (SGLT2 inhibitor)
What this could lead to
If successful, this could point toward a new treatment option for women with chest pain caused by small heart vessel problems, improving their quality of life.
What could go wrong
This is an early Phase 1 trial with only 150 participants, so results may not apply to everyone. The drug may not improve symptoms or could have side effects not yet known.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UVA Health
RECRUITINGCharlottesville, Virginia, 22908, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••