New shot aims to keep Ex-Smokers from lighting up again
NCT ID NCT07223840
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called brenipatide against a placebo to see if it can help adults who have recently quit smoking stay smoke-free. About 222 participants will receive injections for 24 weeks and be followed for 8 more weeks. The main goal is to see if more people remain abstinent from cigarettes with brenipatide than with placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
brenipatide
What this could lead to
If it works, this could offer a new medication to help people who have quit smoking avoid relapsing.
What could go wrong
This is an early Phase 2 trial with only 222 participants, so results may not apply broadly. The drug may not prove more effective than placebo, and side effects are still being studied.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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2nd Affiliated Hospital Chongqing Medical University
RECRUITINGChongqing, 400072, China
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Arch Clinical Trials
RECRUITINGSt Louis, Missouri, 63141, United States
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Beijing Anding Hospital - Affiliated Capital University of Medical Science
RECRUITINGBeijing, 100088, China
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Beijing Chaoyang Hospital, Capital Medical University
RECRUITINGBeijing, 100020, China
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Circle Clinical Research
RECRUITINGSioux Falls, South Dakota, 57104, United States
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Coastal Carolina Research Center
RECRUITINGNorth Charleston, South Carolina, 29405, United States
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Eastside Research Associates
RECRUITINGRedmond, Washington, 98052, United States
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FutureSearch Trials of Dallas
RECRUITINGDallas, Texas, 75251, United States
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GTL Medical & Research Group
RECRUITINGMiami, Florida, 33173, United States
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Health Research of Hampton Roads, Inc.
RECRUITINGNewport News, Virginia, 23606, United States
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Higashi Shinjuku Clinic
RECRUITINGTokyo, 169-0072, Japan
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Hillcrest Medical Research
ACTIVE_NOT_RECRUITINGDeLand, Florida, 32720, United States
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K2 Medical Research ORLANDO
RECRUITINGMaitland, Florida, 32751, United States
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Miyazaki RC Clinic
RECRUITINGShinagawa-ku, 140-0001, Japan
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North Georgia Clinical Research
RECRUITINGWoodstock, Georgia, 30189, United States
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Revival Research Institute, LLC
RECRUITINGDearborn, Michigan, 48126, United States
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Rochester Clinical Research, LLC
RECRUITINGRochester, New York, 14609, United States
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Samoncho Clinic
RECRUITINGShinjuku, 160-0017, Japan
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Sichuan Provincial People's Hospital
RECRUITINGChengdu, 610072, China
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Sir Run Run Shaw Hospital of Zhejiang University School of Medicine
RECRUITINGHangzhou, 310016, China
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Taizhou Hospital of Zhejiang Province
RECRUITINGLinhai, 317000, China
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TecTum Research
RECRUITINGHollywood, Florida, 33024, United States
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The University of Hong Kong-Shenzhen Hospital
RECRUITINGShenzhen, 518053, China
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The University of Texas Health Science Center at Houston
RECRUITINGHouston, Texas, 77054, United States
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The first affiliated hospital of Ningbo university
RECRUITINGNingbo, 315010, China
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Vector Clinical Trials
RECRUITINGLas Vegas, Nevada, 89128, United States
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Woodland Research Northwest
RECRUITINGRogers, Arkansas, 72758, United States
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