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Breathing exercises may boost leg lymphedema treatment

NCT ID NCT07697482

Symptom relief Sponsor: Toros University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study tests whether adding breathing and relaxation exercises to standard lymphedema therapy can improve walking ability and muscle oxygen levels in women with leg swelling. Participants receive either standard therapy alone or standard therapy plus a structured breathing and relaxation program. The goal is to see if these simple additions can enhance functional capacity and muscle health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
respiratory and relaxation training
What this could lead to
If effective, adding simple breathing and relaxation exercises to standard lymphedema therapy could improve walking ability and muscle oxygen levels in patients with leg swelling.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The added exercises may not provide significant benefit over standard therapy alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female patients aged 18 years or older. * Clinically diagnosed with secondary lower extremity lymphedema. * Presence of lower extremity lymphedema for at least 3 months. * Able to stand and walk independently to complete the Six-Minute Walk Test. * Willing and able to provide written informed consent. Exclusion Criteria: * Acute cellulitis or other active infection within the previous 2-4 weeks. * Current or recent deep vein thrombosis (DVT) or uncontrolled peripheral vascular disease. * Severe cardiovascular, pulmonary, orthopedic, or neurological conditions that could interfere with participation or outcome assessments. * Pregnancy. * Skin lesions or irritation preventing placement of the near-infrared spectroscopy (MOXY) sensor. * Inability to comply with the study protocol or follow-up assessments.

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Conditions

The condition(s) this trial relates to.

lymphatic malformation 5 lymphedema primary lymphedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lower extremity lymphedema

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Adana Şehir Eğitim ve Araştırma Hastanesi

    RECRUITING

    Adana, Turkey (Türkiye)

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