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Could a breath of CO2 stop fainting spells?

NCT ID NCT05295810

Recruiting now Symptom relief Sponsor: University of Calgary Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether breathing air with a little extra carbon dioxide can help people with neurogenic orthostatic hypotension (NOH) — a condition where blood pressure drops sharply upon standing, causing dizziness and fainting. Researchers will test this in 80 adults (patients and healthy volunteers) at the University of Calgary. The goal is to see if this simple breathing method can raise blood pressure and improve blood flow to the brain.

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Conditions

The condition(s) this trial relates to.

Hypotension, Orthostatic orthostatic hypotension primary orthostatic hypotension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROGENIC ORTHOSTATIC HYPOTENSION ORTHOSTATIC HYPOTENSION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University of Calgary

    RECRUITING

    Calgary, Alberta, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••