New combo approach for breast cancer: reconstruction and radiation together

NCT ID NCT03627988

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 study looked at women with invasive breast cancer who had a mastectomy with immediate prosthetic breast reconstruction, followed by TomoTherapy (a type of radiation) with or without chemotherapy. The goal was to see how often the reconstruction was successful. 66 patients were followed for up to 3 years. The study measured success rates, treatment quality, and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Mastectomy with immediate prosthetic breast reconstruction and TomoTherapy radiation

What this could lead to

If successful, this approach could offer a safe and effective way to combine breast reconstruction with radiation therapy after mastectomy, improving cosmetic outcomes without delaying cancer treatment.

What could go wrong

This is a small, non-randomized phase 2 study with only 66 participants, so results may not apply to everyone. Complications from surgery or radiation, such as infection or implant issues, are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institut Bergonie

    Bordeaux, France

  • Institut Universitaire Du Cancer de Toulouse - Oncopole

    Toulouse, 31059, France